OPTN/SRTR 2024 Annual Data Report: Overview of US Solid Organ Transplantation

Allyson Hart1,2, David P. Schladt1, Jon J. Snyder1,2,3

1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN

2Department of Medicine, Hennepin Healthcare, University of Minnesota, Minneapolis, MN

3Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN

Abstract

The OPTN/SRTR 2024 Annual Data Report provides information about and trends in solid organ transplantation in the United States from 2013 through 2024. Overall, 2024 data reveal ongoing steady increases in volume; the numbers of patients on waiting lists, transplants performed, and organs recovered in solid organ transplantation all continued to reach record levels, reflecting a mix of ongoing improvements as well as persistent challenges in meeting the needs presented by patients with organ failure. This overview provides information about US solid organ transplantation as a whole, while organ-specific chapters provide more detail on kidney, pancreas, liver, intestine, heart, and lung transplant. These organ-specific chapters generally provide data on both adult and pediatric transplant, as well as descriptive data on waiting lists, transplants (including deceased and living donor transplant when applicable), and patient outcomes. Deceased donor recovery information is presented in a separate chapter, although some organ-specific data on donation are presented in their respective chapters. A brief chapter covers vascularized composite allograft transplant.

Keywords: Organ transplant, patient survival, waiting list

4 Posttransplant Survival

Five-year unadjusted survival remained substantially higher in kidney, liver, pancreas, and heart recipients compared with lung and intestine recipients who underwent transplant in 2017-2019. At 5 years posttransplant, 85.9%, 81.8%, 89.0%, and 80.6% of kidney, liver, pancreas, and heart transplant recipients were alive, respectively (Figure OV 8). However, only 63.3% and 60.0% of intestine and lung transplant recipients were alive after 5 years, respectively.

5 New in This Year’s Annual Data Report

Several new figures and tables have been added in this 2024 Annual Data Report. All organ-specific chapters now contain tables on donor-recipient infectious disease serology matching, figures on candidate active/inactive status, figures and tables on transport distance from donor to candidate, and figures on transplant center counts. The Kidney, Liver, Heart, and Lung chapters have added information about transplant programs and volumes. The Kidney and Liver chapters now include data on living donors over time. The Pancreas and Lung chapters now provide information about posttransplant survival by DCD status, given the recent use of these organs. The Pancreas chapter now includes data on preservation (ie, cold ischemia) time. The Liver chapter now includes data on transplant rates by diagnosis, trends in exception cases, and trends in multiorgan transplant type. The Intestine chapter has added information about congenital versus noncongenital diagnoses. The Heart chapter now contains information about the use of circulatory devices. Finally, the Lung chapter includes added figures reflecting the new allocation scores.

In August of 2024, the Health Resources and Services Administration (HRSA) provided a critical comment letter to the Organ Procurement and Transplantation Network (OPTN) with subsequent direction to develop an analytic definition of allocation out of OPTN sequence (AOOS), which was finalized in June of 2025. Given this critical comment and analytic definition, the 2025 Annual Data Report will include new data regarding trends in AOOS.

6 Summary

Overall, 2024 data reveal ongoing steady increases in volume; the number of candidates on solid organ transplant waiting lists, number of transplants, and number of recovered organs all continue to reach record levels, reflecting a mix of ongoing improvements as well as persistent challenges in meeting the need presented by patients with organ failure. As more “upstream” data are collected prior to waitlisting, future Annual Data Reports will start to describe the ongoing need in more detail, as the current OPTN data provide limited ability to fully assess the unmet need for organ transplant. The organ-specific chapters that follow provide detailed data as well as data relevant to the different organ systems, as each subspecialty strives to improve access to and outcomes after solid organ transplant. However, this high-level overview demonstrates a complex but growing transplant system in the United States, and presents data that highlight ongoing challenges for the transplant community to address.

List of Figures




**All candidates on the kidney or liver waiting list.** Candidates listed at multiple centers are counted once per listing. Includes active and inactive candidates on the list any time during the year.

Figure OV 1: All candidates on the kidney or liver waiting list. Candidates listed at multiple centers are counted once per listing. Includes active and inactive candidates on the list any time during the year.




**All candidates on the waiting list for organs other than isolated kidney or liver.** Candidates listed at multiple centers are counted once per listing. Includes active and inactive candidates on the list any time during the year. PAK, pancreas after kidney; PTA, pancreas transplant alone.

Figure OV 2: All candidates on the waiting list for organs other than isolated kidney or liver. Candidates listed at multiple centers are counted once per listing. Includes active and inactive candidates on the list any time during the year. PAK, pancreas after kidney; PTA, pancreas transplant alone.




**New candidates added to the kidney or liver waiting list during the year.** A new candidate is one who first joined the list during the given year, without having been listed in a previous year. Previously listed candidates who underwent transplant and subsequently relisted are considered new. Candidates listed at multiple centers are counted once per listing. Active and inactive patients are included.

Figure OV 3: New candidates added to the kidney or liver waiting list during the year. A new candidate is one who first joined the list during the given year, without having been listed in a previous year. Previously listed candidates who underwent transplant and subsequently relisted are considered new. Candidates listed at multiple centers are counted once per listing. Active and inactive patients are included.




**New candidates added to the waiting list during the year for organs other than isolated kidney or liver.** A new candidate is one who first joined the list during the given year, without having been listed in a previous year. Previously listed candidates who underwent transplant and subsequently relisted are considered new. Candidates listed at multiple centers are counted once per listing. Active and inactive patients are included. PAK, pancreas after kidney; PTA, pancreas transplant alone.

Figure OV 4: New candidates added to the waiting list during the year for organs other than isolated kidney or liver. A new candidate is one who first joined the list during the given year, without having been listed in a previous year. Previously listed candidates who underwent transplant and subsequently relisted are considered new. Candidates listed at multiple centers are counted once per listing. Active and inactive patients are included. PAK, pancreas after kidney; PTA, pancreas transplant alone.




**Total counts of kidney or liver transplants.** Retransplants and multiorgan transplants are included. Kidney: patients undergoing kidney or simultaneous pancreas-kidney transplant.

Figure OV 5: Total counts of kidney or liver transplants. Retransplants and multiorgan transplants are included. Kidney: patients undergoing kidney or simultaneous pancreas-kidney transplant.




**Total counts of transplants for organs other than isolated kidney or liver.** Retransplants and multiorgan transplants are included. Heart: patients undergoing heart or heart-lung transplant. Lung: patients undergoing lung or heart-lung transplant. Pancreas: patients undergoing pancreas or simultaneous pancreas-kidney transplant.

Figure OV 6: Total counts of transplants for organs other than isolated kidney or liver. Retransplants and multiorgan transplants are included. Heart: patients undergoing heart or heart-lung transplant. Lung: patients undergoing lung or heart-lung transplant. Pancreas: patients undergoing pancreas or simultaneous pancreas-kidney transplant.




**Percentages of organs recovered for transplant and not transplanted.** Percentages of organs not transplanted out of all organs recovered for transplant. Kidneys and lungs recovered en bloc are counted once, and those recovered separately are counted twice.

Figure OV 7: Percentages of organs recovered for transplant and not transplanted. Percentages of organs not transplanted out of all organs recovered for transplant. Kidneys and lungs recovered en bloc are counted once, and those recovered separately are counted twice.




**Patient survival among all transplant recipients, 2017-2019, by organ.** Patient survival estimated using unadjusted Kaplan-Meier methods. Similar overall survival rates for kidney and pancreas recipients and liver and heart recipients may obscure an organ's line on the graph.

Figure OV 8: Patient survival among all transplant recipients, 2017-2019, by organ. Patient survival estimated using unadjusted Kaplan-Meier methods. Similar overall survival rates for kidney and pancreas recipients and liver and heart recipients may obscure an organ’s line on the graph.




**Percentages of DCD transplants by organ.** All transplants, including retransplant and multiorgan. DCD, donation after circulatory death.

Figure OV 9: Percentages of DCD transplants by organ. All transplants, including retransplant and multiorgan. DCD, donation after circulatory death.